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Dr Dianne E. van der Wal

Dianne van der Wal

Senior Research Fellow, Product Development and Storage
 

Dr Dianne E. van der Wal is interested in platelet signalling. Her current project focuses on the platelet responses of apheresis platelet donors.  

During her PhD (Utrecht University, the Netherlands), she demonstrated that novel death pathways were triggered in cold-stored platelets as a result of molecular changes in one of the platelet adhesion receptors.

Some patients suffering from bleeding disorder Immune thrombocytopenia (ITP) are unresponsive to current treatments. In her postdoc in Toronto, Canada, she showed that certain antibodies induced removal of sialic acid leading to platelet clearance by liver macrophages. Therefore, desialylation-inhibitors could possibly be used as a novel drug for ITP.
 

Leadership

Reviewer for ISBT Science Series, Vox Sanguinis and ISBT Congress Abstracts

Chair of session at ISBT Congress, Nusa Dua, 2015
 

Awards

Control of Anticoagulation Travel award

XXIVth Congress of the International Society on Thrombosis and Haemostasis (ISTH), 2013

Abstract Achievement Award

54th Annual Meeting of American Society of Hematology (ASH), 2012

16th Annual LMP Graduate Student Research Day, University of Toronto, 2013

Young Investigator Award

XXIVth Congress of the International Society on Thrombosis and Haemostasis (ISTH), 2013
 

Grants

Personal (Post-doctoral) Fellowship (2+1 years; CAD$90,000) from Canadian Blood Services, Canada, 2011. Unveiling the fundamental differences between anti-GPIbα and anti-GPIIbIIIa-antibody mediated thrombocytopenia: implications for IVIG and alternative therapies.
 

Teaching and supervison

Supervised various research assistants, and Master’s students.

Senior tutor at Monash University, Human Pathology, 3rd year undergraduates.

Practical Tutor at Utrecht University, the Netherlands, for various undergraduate courses.

 

LinkedIn

Other links:
Google Scholar | ResearchGate | Pubmed